@robertov PC seems so personal: I had no palpable lump, PSA 6.x, Gleason 7 but PSMA PET showed lesions in prostate and adjacent lymph nodes. My treatment includes 44 IMRT treatments and 18 months on Orgovyx. @jeffmarc and I have had such extremely different outcomes from treatment: he continues to endure ADT like an athlete and I have been through all the known side effects. I was pre-diabetic (glucose 111) but lost 40 pounds during Covid, pre-diagnosis making all my indicators "normal". Unfortunately, since diagnosis, I've gained back 30 and am pre-diabetic again, and diabetes and stroke are my major fears. I think it's providential that I lost weight earlier. Had I gained 30 with no prior loss, I would definitely be diabetic. ADT has my Testosterone < 10, and life is so different. I had an hour of physical therapy yesterday followed by 2-3 hours of yard work, and I am still "crashed" today. The video doesn't apply to me, but other studies have shown that 18 months ADT is typically as effective as 24 or even 36, so we'll see! I am scheduled to complete ADT at the end of June and am anxious to see whether and how much testosterone returns afterward.