@murirl I hope you figure out the regimen that works best for you. I think most of it for all of us is trial and error, with no one solution that fits everyone. We all usually have other co-morbidities we’re working with as well. For me, the Gabapentin, B12, and a low dose of Magnesium keep me even keel. If I go without either of them, I can feel pain or weakness start to develop. I have had doctors suggest me try other medications, but I’ve been reluctant to change without a clear understanding of what improvements they would make since my current regimen is doing well for me and I’d hate to change and get a different set of problems. If anything would CURE this, I would consider it, but for now I’ve accepted doing what’s best to manage my symptoms.