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Article: Half dose prostate drugs ‘controls cancer minus side effects

Posted by xahnegrey40 @xahnegrey40, Mar 9 9:35am

hope this works as well..would be quite a game changer - reducing standard ADT doseage by half and stopping nasty side effects with same long term results !?

https://www.thetimes.com/uk/healthcare/article/prostate-drugs-side-effects-half-dose-wmd68xmkm

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bht72 | @bht72 | Mar 11 6:56pm
In reply to @jeffmarc "@bht72 Aren’t you also on ADT? That lowers your testosterone and causes most of the hot..." + (show)
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@bht72
Aren’t you also on ADT? That lowers your testosterone and causes most of the hot flash problems.

Yes, Nubeqa can aggravate the problem, but that usually goes away after a short time.

I had severe hot flashes while on ADT. Nubeqa Has not been a problem at all. After eight years on ADT, my hot flashes are what you would call warm flashes and don’t occur very often.

I know dozens of people on Nubeqa And no one reports hot flashes as a problem.

What worked best for me at night was an Embrlabs.com wave 2 device. You can set it to run all night. I used to have the sheet wet under me when I was sleeping because of hot flashes it stopped them.

A Mayo doctor at last month’s monthly meeting posted this information about drugs you can use to stop hot flashes.

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@jeffmarc Thanks for the reply. Yes, I am on ADT. I've been on Nubeqa since November, 25. The hot flashes remain a major issue. I asked my doc about meds to reduce or stop the hot flashes but he cautuioned me they can come with their own side effects. I think everyone just responds differently to these cancer meds. I'll check out the wave device. Thanks again.

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Jeff Marchi | @jeffmarc | Mar 11 6:57pm

In my experience, cutting back on the drugs can be a major mistake for some people.

I was on abiraterone For about a year and a half when I got my oncologist to agree to let me take 750 mg instead of 1000 mg a day. I wanted to see if it would reduce the amount of brain fog I was having. I was getting PSA tests every month, so in the middle of the month, after my last PSA test, I Cut down to 750 mg. That’s not half the drugs that’s 3/4 of the normal medication.

In 19 days, my PSA went from .2 to 1. The only benefit about that was I could get a PSMA PET scan since my PSA was now above .7. I got the scan and immediately Went back on 1000 mg a day. My PSA dropped down to .2 again. I was on Lupron at the time but had become castrate resistant, so Lupron was not keeping my PSA down to undetectable. I also have BRCA2 so that could be a factor.

I wonder what the results will be of this clinical trial. I suspect it won’t work for 100% of the people.

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Jeff Marchi | @jeffmarc | Mar 11 8:46pm
In reply to @bht72 "@jeffmarc Thanks for the reply. Yes, I am on ADT. I've been on Nubeqa since November,..." + (show)
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@jeffmarc Thanks for the reply. Yes, I am on ADT. I've been on Nubeqa since November, 25. The hot flashes remain a major issue. I asked my doc about meds to reduce or stop the hot flashes but he cautuioned me they can come with their own side effects. I think everyone just responds differently to these cancer meds. I'll check out the wave device. Thanks again.

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@bht72
I took depo Provera For four years, a shot every three months. No side effects at all.

Not sure I sent you the list that Mayo recommends. There’s a bunch of different drugs.

Oxybutynin May have some problems with Nubeqa. Ask the doctor.
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