@jeffmarc they said Gleason 2. The urologist surgeon did 15 biopsies, 11 positive. He was “confident” and said they also removed a lymph node (or maybe 2 I’m not sure). We did the PSA 3 months later and showed 1.7, two weeks after that 1.9 so he ordered a pet scan. It lit up in the prostate area so he referred
Me to the radiation oncologist and the medial
Oncologist. I don’t recall
any of your second paragraph wording but I was a little
Overwhelmed at the time too. The surgeon said it could
have gotten outside the prostate and one of the docs made reference to stage 3 which I don’t like the sound of. However, whether it’s just to keep me upbeat or what - the medical and radiation docs were both talking about not planning for the short term but planning for 10 -
20 years out which was a good sign. They did say I would be on Orgovyx 3 years and another pill after radiation. Even with a Medicare supplement it’s about $700 every three months so there are a lot of ups and downs besides the diagnosis.
@mcnite
There is no such thing as Gleason 2. They might’ve said it was grade group 2, which is a Gleason 3+4.
As far as paragraph two goes, You should have a copy of your biopsy report read through it and look for those words in it. It’s that simple.
You say biopsy but also say they removed lymph nodes. That can only be done during surgery not during a biopsy. Did you have prostate cancer surgery?
If 11 of the biopsy cores Were positive what was the Gleason score on each one of those?. You should have a copy of the biopsy report you can look at it and find out the answer.
@mcnite
There is no such thing as Gleason 2. They might’ve said it was grade group 2, which is a Gleason 3+4.
As far as paragraph two goes, You should have a copy of your biopsy report read through it and look for those words in it. It’s that simple.
You say biopsy but also say they removed lymph nodes. That can only be done during surgery not during a biopsy. Did you have prostate cancer surgery?
If 11 of the biopsy cores Were positive what was the Gleason score on each one of those?. You should have a copy of the biopsy report you can look at it and find out the answer.
@jeffmarc i will go back and look at whatever I have. I am a bit overwhelmed with info. If you looked back to my first post, I had a prostatectomy August 12. You know that means the prostate as removed. That was after the biopsies.
@mcnite
There is no such thing as Gleason 2. They might’ve said it was grade group 2, which is a Gleason 3+4.
As far as paragraph two goes, You should have a copy of your biopsy report read through it and look for those words in it. It’s that simple.
You say biopsy but also say they removed lymph nodes. That can only be done during surgery not during a biopsy. Did you have prostate cancer surgery?
If 11 of the biopsy cores Were positive what was the Gleason score on each one of those?. You should have a copy of the biopsy report you can look at it and find out the answer.
@jeffmarc yeah, June 9 biopsies, were either Gleason Grade 3+3=6/10 (Grade Group 1) or Gleason Grade 3+4=7/10 (Grade Group 2 or four were negative.
Not sure where the disconnect is but I was responding to the question about how soon the PSA would go down. They told me it would be good to “talk” to people, I’m not so sure now.
@jeffmarc i will go back and look at whatever I have. I am a bit overwhelmed with info. If you looked back to my first post, I had a prostatectomy August 12. You know that means the prostate as removed. That was after the biopsies.
@jeffmarc that too is confusing medical speak,
PROSTATE AND SEMINAL VESICLES, RADICAL PROSTATECTOMY: - PROSTATIC ADENOCARCINOMA, GLEASON GRADE 3+4 = 7 (GRADE GROUP 2) - CARCINOMA INVOLVES BOTH SIDES OF PROSTATE, AND APPROXIMATELY 15% OF PROSTATIC TISSUE - NON-FOCAL EXTRAPROSTATIC EXTENSION BY CARCINOMA IS IDENTIFIED - BILATERAL SEMINAL VESICLES ARE FREE OF CARCINOMA.
Then I “think” they took 7 lymph nodes and they were negative?
LYMPH NODES, LEFT PELVIC, DISSECTION: FOUR LYMPH NODES, NEGATIVE FOR METASTATIC CARCINOMA (0/4)
LYMPH NODES, RIGHT PELVIC, DISSECTION: - THREE LYMPH NODES, NEGATIVE FOR METASTATIC CARCINOMA (0/3)
@jeffmarc that too is confusing medical speak,
PROSTATE AND SEMINAL VESICLES, RADICAL PROSTATECTOMY: - PROSTATIC ADENOCARCINOMA, GLEASON GRADE 3+4 = 7 (GRADE GROUP 2) - CARCINOMA INVOLVES BOTH SIDES OF PROSTATE, AND APPROXIMATELY 15% OF PROSTATIC TISSUE - NON-FOCAL EXTRAPROSTATIC EXTENSION BY CARCINOMA IS IDENTIFIED - BILATERAL SEMINAL VESICLES ARE FREE OF CARCINOMA.
Then I “think” they took 7 lymph nodes and they were negative?
LYMPH NODES, LEFT PELVIC, DISSECTION: FOUR LYMPH NODES, NEGATIVE FOR METASTATIC CARCINOMA (0/4)
LYMPH NODES, RIGHT PELVIC, DISSECTION: - THREE LYMPH NODES, NEGATIVE FOR METASTATIC CARCINOMA (0/3)
@mcnite
While you have a 3+4 the non-focal EPE Is a serious problem. It would almost be mandatory to be on ADT with this. I am sure your doctor will talk to you about it.
More information
Non-focal extraprostatic extension (EPE) in prostate cancer means cancer has spread extensively beyond the prostate capsule into surrounding fatty tissue, typically covering more than one or two microscopic sections (often defined as >1 high-power field). It signifies a more aggressive tumor, higher risk of biochemical recurrence (BCR), and poorer outcomes than focal EPE.
At this point, I would want to ask the doctor were the margins clear. I don’t suppose they are because EPE says it has spread extensively beyond the prostate. You need to speak to the doctor about recommendations for the near future.
@mcnite
While you have a 3+4 the non-focal EPE Is a serious problem. It would almost be mandatory to be on ADT with this. I am sure your doctor will talk to you about it.
More information
Non-focal extraprostatic extension (EPE) in prostate cancer means cancer has spread extensively beyond the prostate capsule into surrounding fatty tissue, typically covering more than one or two microscopic sections (often defined as >1 high-power field). It signifies a more aggressive tumor, higher risk of biochemical recurrence (BCR), and poorer outcomes than focal EPE.
At this point, I would want to ask the doctor were the margins clear. I don’t suppose they are because EPE says it has spread extensively beyond the prostate. You need to speak to the doctor about recommendations for the near future.
@jeffmarc ok. I think that’s what the Orgovyx is? ADT? I am to start 39 weeks of radiation next and then another pill (?) on top of Orgovyx. Thanks for the info, I have more knowledge to inquire with them.
@jeffmarc ok. I think that’s what the Orgovyx is? ADT? I am to start 39 weeks of radiation next and then another pill (?) on top of Orgovyx. Thanks for the info, I have more knowledge to inquire with them.
@mcnite
Yes, Orgovyx is ADT. It’s also a little bit easier with side effects.
Yes, you should be on another pill besides Orgovyx. That’s an ARPI, that includes Zytiga or one of the lutamides.
What you have is aggressive, so you need to treat it aggressively. One good advantage of being on the second pill is that it prevents the ADT from making you become castrate resistant Sooner.
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I started with a base PSA of 143 in December and started with Ogovyx in January PSA February 1st 9.5, March 1st -2.4.
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There is no such thing as Gleason 2. They might’ve said it was grade group 2, which is a Gleason 3+4.
As far as paragraph two goes, You should have a copy of your biopsy report read through it and look for those words in it. It’s that simple.
You say biopsy but also say they removed lymph nodes. That can only be done during surgery not during a biopsy. Did you have prostate cancer surgery?
If 11 of the biopsy cores Were positive what was the Gleason score on each one of those?. You should have a copy of the biopsy report you can look at it and find out the answer.
@jeffmarc i will go back and look at whatever I have. I am a bit overwhelmed with info. If you looked back to my first post, I had a prostatectomy August 12. You know that means the prostate as removed. That was after the biopsies.
@jeffmarc yeah, June 9 biopsies, were either Gleason Grade 3+3=6/10 (Grade Group 1) or Gleason Grade 3+4=7/10 (Grade Group 2 or four were negative.
Not sure where the disconnect is but I was responding to the question about how soon the PSA would go down. They told me it would be good to “talk” to people, I’m not so sure now.
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I also had a prostatectomy. Look for the biopsy after the surgery, the biopsy of the prostatectomy that tells the most.
@jeffmarc that too is confusing medical speak,
PROSTATE AND SEMINAL VESICLES, RADICAL PROSTATECTOMY: - PROSTATIC ADENOCARCINOMA, GLEASON GRADE 3+4 = 7 (GRADE GROUP 2) - CARCINOMA INVOLVES BOTH SIDES OF PROSTATE, AND APPROXIMATELY 15% OF PROSTATIC TISSUE - NON-FOCAL EXTRAPROSTATIC EXTENSION BY CARCINOMA IS IDENTIFIED - BILATERAL SEMINAL VESICLES ARE FREE OF CARCINOMA.
Then I “think” they took 7 lymph nodes and they were negative?
LYMPH NODES, LEFT PELVIC, DISSECTION: FOUR LYMPH NODES, NEGATIVE FOR METASTATIC CARCINOMA (0/4)
LYMPH NODES, RIGHT PELVIC, DISSECTION: - THREE LYMPH NODES, NEGATIVE FOR METASTATIC CARCINOMA (0/3)
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1 Reaction@mcnite
While you have a 3+4 the non-focal EPE Is a serious problem. It would almost be mandatory to be on ADT with this. I am sure your doctor will talk to you about it.
More information
Non-focal extraprostatic extension (EPE) in prostate cancer means cancer has spread extensively beyond the prostate capsule into surrounding fatty tissue, typically covering more than one or two microscopic sections (often defined as >1 high-power field). It signifies a more aggressive tumor, higher risk of biochemical recurrence (BCR), and poorer outcomes than focal EPE.
At this point, I would want to ask the doctor were the margins clear. I don’t suppose they are because EPE says it has spread extensively beyond the prostate. You need to speak to the doctor about recommendations for the near future.
@jeffmarc ok. I think that’s what the Orgovyx is? ADT? I am to start 39 weeks of radiation next and then another pill (?) on top of Orgovyx. Thanks for the info, I have more knowledge to inquire with them.
@mcnite
Yes, Orgovyx is ADT. It’s also a little bit easier with side effects.
Yes, you should be on another pill besides Orgovyx. That’s an ARPI, that includes Zytiga or one of the lutamides.
What you have is aggressive, so you need to treat it aggressively. One good advantage of being on the second pill is that it prevents the ADT from making you become castrate resistant Sooner.
My PSA dropped 50% (6.x to 3.x) in the six weeks I took it before beginning radiation.
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