@mrmacabre Good morning and thanks for your thoughts.About 12 years ago I was prescribed 900 milligrams of Gaba,and 60 milligrams of Duloxetine,not a word was mentioned about dependency or withdrawl. the combo put me to sleep for a couple of weeks but did take the edge off.Not being very sophisticated with a laptop,I never looked into these issues,I just took the pills every day,I thought Duloxetine was just a light weight additive to the Gaba,so I found myself treating myself for major depression and anxiety without even knowing it,I am the anxious type,I didnt recognize how it made me feel at the time,because I wasnt informed