@llthomson Thanks for communicating back. Here's my take on the "delay things 6 months for every 18 months." And thank you for explaining. I never saw that article. Any ADDITIONAL extra valuable time with our spouses is worth it, but I think as important, my husband, with JOYFUL HOPE was all in when he chose to do the lequembe infusions. For us, we saw no other way, than to do it, and have faith that some progress would be made. None of know the outcome of our life. And anything we can do to help slow this disease down in our minds was worth doing. He was hopeful, and that hope every day, comes out in the joyful way he is still living his life. Even though he forgets, and we have minor meltdowns through the day, I can tell making the lequemebe decision was good for him, and gave him the inner resolve to "try to beat the outcome" if that's possible. . Maybe that's the way he chose to handle things quietly initially, but I notice this upbeat resolve to just do what he needs to do, which I know makes him feel better every day. When he talks to his son about how he's feeling, he's calm and joyful. A positive mind can conquer many things. Maybe not get rid of something genetic but can give us the courage to move through the day, the clarity in the decisions and lifestyle changes we now have to make, and trusting in God's light to show us the way. I keep saying "We are not alone" and for me in all of this, that is powerful and comforting.