I experienced fatigue for about 2-3 days after my most recent infusion. I was fine after that. During the past infusions, I was able to work-out in the afternoons after completing each of the first three cycles. I had GI issues that lasted a few days after each treatment, nothing that required more than over the counter stool sofeners. I would also recomend that you drink a LOT of fluids. Exercising , if possible, is also benefitial.
I am sure that you are in very good hands with Mayo, Still, do not be afraid to ask questions until you are comfortable with their answers.
Are you doing Bendamustine and Rituximab? Will you be receiving any meds for possible increases in Uric acid as well as viral infections?
If you have not already done so you might want to check-out the International WM Foundation website.