I started my infusion treatment in November of 2025 after a period of watch and wait. First, I will share with you what I had been told; everyone reacts differntly to treatment. So my experience may be different than what you will experience. It is also been often repeated " when you meet one person with WM, you have met one person with WM". Meaning, everyone's WM symtoms may be different, how they react and respond to treatment also varies.
Hopefully your treatment team is knowledgeable about WM. If so, they have gone over in detail the infusion process, reviewed possible side effects that could occur during the treatment as well as after the infusion possible side effects. They should also have prescribed recomended drugs that help to combat possible side effects. Ask questions of your team so that you comfortable with the entire process and you and your spouse are better prepared.
In my case, I have not had any negative reaction to the B/R infusions. My side effects after infusion have been minimal, some fatigue and GI issues. Prior to my treatment, I tried to get as informed as possible. I joined this forum as well as the IWMF forum. My wife and I had discussions with my treatment team concerning treatment options and the treatment process. We also sought a second opinion with another doctor to discuss those options. There are also support groups.
Best of luck and stay positive.