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@shail —I would recommend Raloxifene instead of tamoxifen as it helps your bones and protects against breast cancer with fewer side effects. It mimics estrogen's effects in the bones to prevent bone thinning and strengthening them (especially the spine) and at the same time blocks the effects of estrogen on breast tissue, reducing the risk of developing invasive breast cancer.

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Replies to "@shail —I would recommend Raloxifene instead of tamoxifen as it helps your bones and protects against..."

@maymore :

Hi! Maymore:

Thanks for sharing such useful information regarding the effects of the medication, Raloxifene (Evista)!

I am wondering whether we may ask our medical oncologists to prescribe Raloxifene instead of any AIs? As I understand it, Raloxifene is a selective estrogen receptor modulator (SERM), used to prevent and treat osteoporosis and reduce invasive breast cancer risk in postmenopausal women, and it also strengthens bones and blocks estrogen in breast tissue. This brings me some new hope, for I've been struggling with severe spinal issues lately. Has anybody tried this medication instead of any AIs? If you have, could you please share your personal experiences after taking it?

Thank you for your comments and better journey ahead, my comrades in fighting the disease of cancer!

@maymore Isn't Raloxifene, (Evista) primarily an osteoporosis drug? I don't think it's approved for invasive breast cancer treatment. It is only used as a prevention. Yes, fewer side effects than Tamoxifen but still has risk of blood clots. Of course, we can each make our on treatment decisions, whether drug is approved or not. But it might be hard finding an oncologist to prescribe Raloxifene for invasive breast cancer.