Have brain fog? Mayo & ASU study seeking breast cancer survivors
Have you completed breast cancer treatment but still experience lingering “brain fog,” trouble focusing, or mental fatigue?
Researchers at Mayo Clinic and Arizona State University are inviting women to participate in an online 10-week research study exploring a lifestyle program designed to support cognitive recovery after cancer treatment.
This nationwide research study, called RESTORE, looks at whether longer overnight fasting can help improve sleep and thinking (cognition) in breast cancer survivors. The study takes place online.
Who can take part
You may be able to take part if you:
- Are a woman age 18 or older
- Have been diagnosed with breast cancer
- Have completed chemotherapy (if you received it)
- Finished your last neoadjuvant or adjuvant chemotherapy at least 3 months ago
- You do not need to be a Mayo Clinic patient
What you will do
Participation is completely voluntary.
- The study lasts 10 weeks and is completed online
- Track when you start and stop eating for 14 days
- Be randomly placed into one of two groups for 8 weeks:
- A nightly fasting group
- A health education group
- Complete online Zoom sessions before and after the study to share health information
Compensation
- All participants can receive up to $75 in gift cards
- Participants in the nightly fasting group who complete a 20‑minute exit interview may receive an additional $25 gift card
Interested?
If you are interested in taking part in the study, please complete this online form https://links.asu.edu/restore_study
Questions? Contact the research study team:
- Study phone: (602) 496‑8248
- Study email: RestoreStudy@asu.edu
- Principal Investigator contact: james.sarah1@mayo.edu
Interested in more discussions like this? Go to the Breast Cancer Support Group.
Connect

Hi! Colleen:
Thanks for passing the information regarding this interesting research study, "RESTORE"!
Could you please let us know the results of this research study when it has been completed, please? I am not eligible to participate in this project because I am currently still in the midst of my treatment plan; but I am very interested to know what the conclusion of this national study shall be.
Thank you so much for helping us!
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1 ReactionThanks Colleen. I have registered.
I am experiencing brain fog, receiving feedback at work when it happens. Its tough to hear but I am sharing with friends and colleagues, why it happens due to treatment.
@malebreastcancer47 Thank you for contacting us for the study. This study is evaluating adult women but the study team hopes to be able to do an expanded and larger study of this issue in the future.
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1 Reaction@saraheja I received an email saying I could not participate. I was bummed.
Its interesting how blocking estrogen works, and its side effects in women vs men.
Look forward to participating in future. I am on Tamoxifen for 4 more years.
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1 Reaction@malebreastcancer47 how long did it take for them to respond? I have not heard anything yet…. It’s been almost a week.
@justabumpintheroad Within an hour.
I shared with my Mayo oncology team of the brain fog. After I had a physical this week and labs, turns out the brain fog could be attributed to low Vitamin D. I have been taking but its not enough. My PCP at Northwestern Medical, suggested Vitamin D + K2.
Mayo also suggested acupuncture, per a recent research study that showed improvement in cognition. They also said to do yoga and meditation.
I think being on Tamoxifen 10mg, the side effects are far less but due to estrogen blocking, safe to say deficiencies in other areas your body needs is also possible.
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2 Reactions@justabumpintheroad, have you heard back from the study team? If not, please contact the research study team again:
Study phone: (602) 496‑8248
Study email: RestoreStudy@asu.edu