Hi @lewismustard I can understand that worry. It all depends on the type of insulin, long acting or short acting. There is an insulin which is used once a day by most folks called Lantus. That is usually used pm but some doctors may prescribe it earlier. Most likely Consumer Reports has done a review of glucometers. All I know is that they are costly. Companies offer the machines for free with the initial control solution and test strips. After that the consumer is responsible for the maintenance i.e. to purchase more control solution and test strips. It can get expensive. Toni