I was taking a trial of Lyrica a few years ago and one day became incoherent. I couldn't finish a sentence. ER admitted me for 3 days and figured out that I was reacting to Lyrica. Unfortunately, it was the only medication that ever helped my PN pain. It was a bummer that I couldn't tolerate it!
@jimhd One drug was useless for me, one was as brain numbing as tramadol and Lyrica, even a high does is not brain numbing and is effective for my pain. Unfortunately, I experience Lyrica troughs that require more frequent dosing. It is critical to work with your doctors through some trial and error on medicines and dosing.
I have worked with PCPs, pain specialists, neurologists, psychiatrists, clinics, searching for a medication that relieves my PN pain. I've tried dozens of medications, some did nothing, some caused cognitive issues, others had unacceptable side effects. MS Contin helped for a number of years, but my PCP cut back my dosage to a level that was non therapeutic. Hizentra has reduced the pain from 8-9 to 4-5, which is bearable. I wish I had been able to tolerate Lyrica.
Have had PN for at least 20 years- not diabetic but lower back injury in my younger days considered to be my problem (now 85)
Take pregagalin (Lyrica)100mg after evening meal prior to bed time /no medication during the day and yes some days if I dont rest occasionally it can be somewhat painful - most nights this is enough Lyrica to allow a reasonable night’s sleep. I am Australian and appreciate Mayo Clinic to allow me to be involved. — John G
Have had PN for at least 20 years- not diabetic but lower back injury in my younger days considered to be my problem (now 85)
Take pregagalin (Lyrica)100mg after evening meal prior to bed time /no medication during the day and yes some days if I dont rest occasionally it can be somewhat painful - most nights this is enough Lyrica to allow a reasonable night’s sleep. I am Australian and appreciate Mayo Clinic to allow me to be involved. — John G
Welcome @johnglass, Thanks for sharing your experience with Lyrica. I'm almost 83 and have been dealing with PN for close to 45 years but just have numbness in the feet and legs and degenerative arthritis pain. Fortunately I don't have to take medication for the pain other than a few topicals for the arthritis pain. Glad that you found Connect. The Connect search function is great if you want to locate other members with specific conditions or symptoms.
I have been taking pregalbin 150 mg per day, as prescribed by an expert neurologist some years ago. This was after extensive tests at a neurology lab. The neurologist told me that she knew of no cure for my neurapathy. It has been getting steadily worse, but the discomfort is reduced with 100 mg tramadol per day.
I have recently started with magnesium glycinate and it seems to help.
Taking the pregalbin at bedtime gives me a good night's sleep, but I wake up quite disoriented. My GP says that this is acceptable, and I find that I am only fitfully asleep without the pregalbin.
I am 85 years old and have cervical stenosis as well as arthritis in my back, so the tramadol is supplemented with Celebrex.
I find that gentle foot massage and pedicure helps a bit, but I warn against vigourous foot massage because it seems to inflame the neurapathy for a couple of days afterwards. I also have an electical foot massager that I bought for about $100 from Amazon, It has a heater that gives me some relaxation, but doesn't reduce the numbness in my calves and feet.
I have been taking pregalbin 150 mg per day, as prescribed by an expert neurologist some years ago. This was after extensive tests at a neurology lab. The neurologist told me that she knew of no cure for my neurapathy. It has been getting steadily worse, but the discomfort is reduced with 100 mg tramadol per day.
I have recently started with magnesium glycinate and it seems to help.
Taking the pregalbin at bedtime gives me a good night's sleep, but I wake up quite disoriented. My GP says that this is acceptable, and I find that I am only fitfully asleep without the pregalbin.
I am 85 years old and have cervical stenosis as well as arthritis in my back, so the tramadol is supplemented with Celebrex.
I find that gentle foot massage and pedicure helps a bit, but I warn against vigourous foot massage because it seems to inflame the neurapathy for a couple of days afterwards. I also have an electical foot massager that I bought for about $100 from Amazon, It has a heater that gives me some relaxation, but doesn't reduce the numbness in my calves and feet.
@llanfi
Thanks Mary for all of the additional information you provided on your health history.
I have had neuropathy for approximately 7 years it has mostly remained in my numb feet. I also have severe Osteoarthritis. Over the years , I was uncertain as to what caused my pain. A long story of search entailed, much too long for this message. I will soon arrive at my 79th birthday and was extremely active in Playing pickleball until June of this year. I honestly have found most doctors to be of no help, when it comes to the above issues. Perhaps a Neurologist may be helpful if the neuropathy progresses. What seems to help me the most , is to insure that I keep moving at least 2,500 steps a day. I have restarted using Gabepetin 300 mg. 2 of 3 times per day. I felt that my first try, not enough time was spent 30 days to accurately judge its effectiveness. This time I intend to try at least 60 days.
If you have severe pain, you may
want to discuss with a pain management facility in your area
SCS Spinal Cord Stimulus ((Implant) it’s available as a five day external trial to determine its effectiveness. We each gave our own long pain history, so it’s hard to condense it into a small summary. Also, I am currently involved with a health care advocate , who stays in regular contact with me from an organization called ( Solace)
This advocate helps me through the maze of health care to find or discuss solutions. If you don’t have an advocate, This may be a very helpful avenue for you to connect with. I believe it is a no charge service.
If you have any questions, please feel free to communicate with me.
God bless in your pursuit of pain relief. Best Regards,
Gene
I have been taking pregalbin 150 mg per day, as prescribed by an expert neurologist some years ago. This was after extensive tests at a neurology lab. The neurologist told me that she knew of no cure for my neurapathy. It has been getting steadily worse, but the discomfort is reduced with 100 mg tramadol per day.
I have recently started with magnesium glycinate and it seems to help.
Taking the pregalbin at bedtime gives me a good night's sleep, but I wake up quite disoriented. My GP says that this is acceptable, and I find that I am only fitfully asleep without the pregalbin.
I am 85 years old and have cervical stenosis as well as arthritis in my back, so the tramadol is supplemented with Celebrex.
I find that gentle foot massage and pedicure helps a bit, but I warn against vigourous foot massage because it seems to inflame the neurapathy for a couple of days afterwards. I also have an electical foot massager that I bought for about $100 from Amazon, It has a heater that gives me some relaxation, but doesn't reduce the numbness in my calves and feet.
@llanfi I am starting lyrica Monday have been on gabapentin no luck. Used mirage for restless leg for over thirty years, have to ween off before going to lyrica. Hopefully it will help both a little. Have had three back surgeries to no avail and the stimulator in the spine to no good results. 84 and get 2 to four hours sleep at night, not good
@llanfi I am starting lyrica Monday have been on gabapentin no luck. Used mirage for restless leg for over thirty years, have to ween off before going to lyrica. Hopefully it will help both a little. Have had three back surgeries to no avail and the stimulator in the spine to no good results. 84 and get 2 to four hours sleep at night, not good
@datsun66
Not certain who is or was on Gabapetin. However dosage of 150 mg. Seems extremely low. I’m back on for a longer trial period since I wasn’t told that it would t kick in u til 30-35 days. Current dosage is 2-3 times daily with 300 mg.
I am 79, with neuropathy localized in my numb feet for the past 7 years. Now combined with Severe Osteoarthritis. I will be searching this community for people who have Neuropathy, and have undergone a total knee replacement. My concern is having g a TKR will cause my Neuropathy to be more affected , don’t need or want more neuropathy areas. I sleep well, can still walk albeit with pain.
I make myself move every day with a minimum step count of 2500. I would like to hear from any person who has had TKR with Neuropathy.
Best Regards, Gene
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@jimhd One drug was useless for me, one was as brain numbing as tramadol and Lyrica, even a high does is not brain numbing and is effective for my pain. Unfortunately, I experience Lyrica troughs that require more frequent dosing. It is critical to work with your doctors through some trial and error on medicines and dosing.
I have worked with PCPs, pain specialists, neurologists, psychiatrists, clinics, searching for a medication that relieves my PN pain. I've tried dozens of medications, some did nothing, some caused cognitive issues, others had unacceptable side effects. MS Contin helped for a number of years, but my PCP cut back my dosage to a level that was non therapeutic. Hizentra has reduced the pain from 8-9 to 4-5, which is bearable. I wish I had been able to tolerate Lyrica.
Jim
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1 ReactionHave had PN for at least 20 years- not diabetic but lower back injury in my younger days considered to be my problem (now 85)
Take pregagalin (Lyrica)100mg after evening meal prior to bed time /no medication during the day and yes some days if I dont rest occasionally it can be somewhat painful - most nights this is enough Lyrica to allow a reasonable night’s sleep. I am Australian and appreciate Mayo Clinic to allow me to be involved. — John G
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4 ReactionsWelcome @johnglass, Thanks for sharing your experience with Lyrica. I'm almost 83 and have been dealing with PN for close to 45 years but just have numbness in the feet and legs and degenerative arthritis pain. Fortunately I don't have to take medication for the pain other than a few topicals for the arthritis pain. Glad that you found Connect. The Connect search function is great if you want to locate other members with specific conditions or symptoms.
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3 Reactions@maryrdavis
Hi Mary : So where is your Neuropathy located?
Gene
@gjuszaki in my legs and feet. Especially left side.
I have been taking pregalbin 150 mg per day, as prescribed by an expert neurologist some years ago. This was after extensive tests at a neurology lab. The neurologist told me that she knew of no cure for my neurapathy. It has been getting steadily worse, but the discomfort is reduced with 100 mg tramadol per day.
I have recently started with magnesium glycinate and it seems to help.
Taking the pregalbin at bedtime gives me a good night's sleep, but I wake up quite disoriented. My GP says that this is acceptable, and I find that I am only fitfully asleep without the pregalbin.
I am 85 years old and have cervical stenosis as well as arthritis in my back, so the tramadol is supplemented with Celebrex.
I find that gentle foot massage and pedicure helps a bit, but I warn against vigourous foot massage because it seems to inflame the neurapathy for a couple of days afterwards. I also have an electical foot massager that I bought for about $100 from Amazon, It has a heater that gives me some relaxation, but doesn't reduce the numbness in my calves and feet.
-
Like -
Helpful -
Hug
1 Reaction@llanfi
Thanks Mary for all of the additional information you provided on your health history.
I have had neuropathy for approximately 7 years it has mostly remained in my numb feet. I also have severe Osteoarthritis. Over the years , I was uncertain as to what caused my pain. A long story of search entailed, much too long for this message. I will soon arrive at my 79th birthday and was extremely active in Playing pickleball until June of this year. I honestly have found most doctors to be of no help, when it comes to the above issues. Perhaps a Neurologist may be helpful if the neuropathy progresses. What seems to help me the most , is to insure that I keep moving at least 2,500 steps a day. I have restarted using Gabepetin 300 mg. 2 of 3 times per day. I felt that my first try, not enough time was spent 30 days to accurately judge its effectiveness. This time I intend to try at least 60 days.
If you have severe pain, you may
want to discuss with a pain management facility in your area
SCS Spinal Cord Stimulus ((Implant) it’s available as a five day external trial to determine its effectiveness. We each gave our own long pain history, so it’s hard to condense it into a small summary. Also, I am currently involved with a health care advocate , who stays in regular contact with me from an organization called ( Solace)
This advocate helps me through the maze of health care to find or discuss solutions. If you don’t have an advocate, This may be a very helpful avenue for you to connect with. I believe it is a no charge service.
If you have any questions, please feel free to communicate with me.
God bless in your pursuit of pain relief. Best Regards,
Gene
@llanfi I am starting lyrica Monday have been on gabapentin no luck. Used mirage for restless leg for over thirty years, have to ween off before going to lyrica. Hopefully it will help both a little. Have had three back surgeries to no avail and the stimulator in the spine to no good results. 84 and get 2 to four hours sleep at night, not good
@datsun66
Not certain who is or was on Gabapetin. However dosage of 150 mg. Seems extremely low. I’m back on for a longer trial period since I wasn’t told that it would t kick in u til 30-35 days. Current dosage is 2-3 times daily with 300 mg.
I am 79, with neuropathy localized in my numb feet for the past 7 years. Now combined with Severe Osteoarthritis. I will be searching this community for people who have Neuropathy, and have undergone a total knee replacement. My concern is having g a TKR will cause my Neuropathy to be more affected , don’t need or want more neuropathy areas. I sleep well, can still walk albeit with pain.
I make myself move every day with a minimum step count of 2500. I would like to hear from any person who has had TKR with Neuropathy.
Best Regards, Gene