Yes. I have Myelofibrosis “and” Erdheim Chester Disease, and the first sign - although no doctor attributed it correctly at the time - was uncontrollable thoracic itching. It has since stopped, probably because the disease evolved into a later stage. But, what stopped my itching episodes almost instantly whenever they occurred was Xanax. Why? I don’t know. But, when you’re itching, and you want to jump from the roof to make it stop, you don’t care. Xanax does it. .25 mg per day is what I’m on now.