Has anyone had HUGE swings up and down in GFR over time ?

Thank you for the response. 1. I will most definitely continue to follow the healthy lifestyle. 2. I do not trust my physicians, several reasons, one example - two weeks ago I visited my Urologist, when the blood was drawn for this latest lab, it was a Comprehensive Metabolic Panel, and as indicated in my original post the eGFR was 53, based on creatinine. During that visit, I asked the Urologist his opinion on doing a C - Cystatin eGFR test to get a more steady eGFR result, as it’s my understanding that the C-Cystatin test is influenced by less factors. He responded “ a what test?” . I said a C - Cystatin eGFR test and showed him on my phone what it was. He said “ I have never even heard of that test”. This is a board certified Urologist, with 20 years experience, at the largest Urology practice in Florida, USA. ????? 3. I do not yet have a nephrologist, I have an appointment with one in 2 months, ( I just made it, first available date). 4. I will definitely look into a second opinion from a transplant center. 5. I do not think I am a candidate for dialysis treatment or a transplant list, from my research, but I am already looking for a living donor.

@faithfully123 I have every confidence in my doctor, Lieske, at Mayo, Rochester. My swings historically were much worse than yours. I am always amazed how much kidney numbers vary. However, you can ease your mind some that you are not in the replacement number area. I found that a low oxalate diet combined with calcium at each meal helped my stones, which were much smaller than yours and blocked my tubules. Between Mayo’s Dietition and using an oxalate list from Harvard’s Chan school I was able to make real changes in my health.

I have just read that the FDA has approved 5 new drugs for kidney treatment hopefully this will benefit all of us. I raised my eGFR about 10 points by drinking lots of water. B/4 I was never a water drinker but this came along and now I am a believer. My certainties went from 1.81 to 1.50.

@rrr1952 Thanks so much. I also hope the new drugs do benefit all of us. Full Hydration is one of my main goals every day.

@faithfully123 Hydrate but do not overhydrate. I just got out of the hospital for stroke-like symptoms from what I am convinced was hyponatremia ( too much water causing a salt imbalance leading to brain swelling).

@cdammen I am sorry to hear you were hospitalized, and I hope you are okay now. I agree 100%. In my blood work the past year, I have had borderline low sodium and low chloride, from over hydration. Now, I use Pedialyte for the electrolytes, I don’t know if it works. Damned if we under hydrate, damned if we over hydrate. It’s such a fine balance. Prayers.

I have just read that the FDA has approved 5 new drugs for kidney treatment hopefully this will benefit all of us. I raised my eGFR about 10 points by drinking lots of water. B/4 I was never a water drinker but this came along and now I am a believer. My certainties went from 1.81 to 1.50.