@oopsiedaisy thanks for the clarification. So, did you switch to Evenity because you were suffering side effects from the Tymlos and/or Forteo? I'm currently on Forteo and like you don't yet know if it's helped. Assuming I've had good gains I plan to follow up with Reclast for a year or 2, at which time I hope to go on a drug holiday, even if I have to go back on something eventually. Like you, I hope to avoid spending the rest of my life on osteoporosis meds. @shorty321 I know my responses haven't addressed your question and went off on a little tangent so I apologize for that. I don't have an answer unfortunately and I'm not sure doctors do either, except to just keep switching to different drugs when we hit the time limit on each one. Maybe the best we can do is get a drug holiday between drugs and keep an eye on DEXAs to know when we need to start up with something again.