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fritzo avatar

Decipher risk: prostatectomy RP vs radiation.

Prostate Cancer | Last Active: Mar 14 11:09am | Replies (75)

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Profile picture for K. J. HOLZ @kjholz

Hi fritzo @fritzo,

re: you writing "It sounds like it is rare for most to have Decipher test information prior to a RP since it is a tool for accessing radiation options."

Sorry but Decipher is not a tool for accessing radiation options. It tells you how aggressive a particular cancer is. And yes, at a certain aggressive point, Decipher can help your doctor decide whether to add ADT atop the radiation.

The only test that I know of for assessing radiation options is PROSTOX. PROSTOX helps identify your risk levels "for developing Grade ≥2 or higher late genitourinary TOXICITY after prostate directed treatment."

PROSTOX Ultra tells you whether you are Low or High Risk for SBRT. And PROSTOX Standard reports Low or High Risk for CFRT (IMRT). The ideal is to score Low on both tests bc you are free to choose either SBRT or IMRT. If you score High on one of the tests and Low on the other, you still have a radiation path.

But! About 1-2% score HIGH RISK on both PROSTOX tests! We did! And the radiation door was slammed shut! I asked my husband whether he regretted getting the test. He responded immediately with "Absolutely not!"

He has an existing "weak stream" score on the International Prostate Symptom Score (IPSS) test of "5". That kind of "weak stream" plus a Double HIGH RISK for radiation!? ...yeahNO.

That said, prostatectomy is out too....

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Replies to "Hi fritzo @fritzo, re: you writing "It sounds like it is rare for most to have..."

@kjholz They say information is power, but I guess it doesn't make life any easier.

I actually randomly found the Prostox test online and mentioned it my radiaiton oncologist, who wasn't aware of it, but said he was open to it and would evaluate if he should offer it to others.

In the process, things got flipped and the nurse had me initiate the paperwork, which meant I was paying up front. However, based on income and debt, the Prostox financial form reduced my out-of-pocket payment for the CFRT (IMRT) to only $100 instead of $500. So very appreciative. I didn't do both tests because I wasn't looking at SBRT at that point. I was fortunate that my Prostox test result was very low risk....but with the Decipher score being high risk, meaning radiation plus hormone therapy, I'm locking in on surgery. Still not a sure thing. Good luck to both of you finding a path.