@sirene
frequently the problem with estrogen cream are the additives and the base.

Versa Base is a good base to try for those of us with reactive tissue.

But.... here is a listing from google of what additives and base to try or lose:
"While VersaBase is already designed to be hypoallergenic, irritation in sensitive vaginal or vulvar tissue is often triggered by specific secondary additives. Eliminating the following common culprits from your compounded formula can significantly reduce the risk of burning or itching:
Propylene Glycol (PG): This is one of the most frequent causes of vaginal burning in commercial products like Estrace. VersaBase is formulated to be Propylene Glycol-free by default.
Parabens: These preservatives (like methylparaben or propylparaben) are common allergens and can disrupt the vaginal microbiome. VersaBase is paraben-free.
Glycerin: While a humectant, glycerin can sometimes feed Candida albicans, potentially increasing the risk of yeast infections, which lead to secondary irritation.
Fragrances & Dyes: These offer no therapeutic benefit and are high-risk triggers for contact dermatitis in the vulvovaginal area."

Also, Sirene, your compounding pharmacist may be able to make up a hyaluronic acid suppository, at a very affordable price point, with a script from your doctor. I even third or quarter my HA suppository which is an even better price point. 🙂