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Sputum Test submissions and outcome results

MAC & Bronchiectasis | Last Active: Feb 26 7:09pm | Replies (81)

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Profile picture for Sue, Volunteer Mentor @sueinmn

@annagh If I understand the trials correctly, this will be a game changer. The literature I found searching on Google Scholar is of preliminary trials, the most detailed occurring in 2022. Unfortunately recent research seems to be going in a familiar direction - focusing on the far more common M. Tuberculosis.
I looked for clinical trials of the test and found that there is possibly one in progress in Oregon.

Did your doctor provide any additional information?

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Replies to "@annagh If I understand the trials correctly, this will be a game changer. The literature I..."

@sueinmn I am in the trial at OHSU, and very hopeful that this will be helpful to all of us.
Protocol Title: CRISPR detection of circulating cell-free Mycobacterium avium complex (MAC) DNA for rapid diagnosis and monitoring of MAC pulmonary disease (CRISPR) and Mycobacterium avium complex pulmonary infection: immunologic and transciption signatures of disease and treatment response (IMMTR)
Protocol #: NTM CRISPR IMMTR
Sponsor: NIDID (National Institute of Allergy and Infectious Diseases)
Principal Investigator: Kevin Winthrop, MD, MPH
Institution: OHSU
Purpose: The purpose of the study is to learn more about how CRISPR technology can be used to detect MAC in your blood and improve diagnosis and monitoring of MAC pulmonary disease.
Anna