My Rheumatologist diagnosed me with Inflammatory Arthritis and Osteoarthritis. I had an elevated SED rate but no other inflammatory markers. She waited for a year to diagnose it as seronegative RA. I started on Methotextrate then added Plaquenil. Then went to Enbrel injections. Now I aj on Orencia infusions with great success. I was on and off Prednisone (5-10 mg) for 4 years. I have been off for 4 months now. I really miss it but I know the side effects are not good. The OA is my worst complaint now I think.