← Return to Oxybutynin superior to placebo in reducing ADT-associated hot flashes

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Profile picture for Jeff Marchi @jeffmarc

Oxybutynin is one solution. I got depo-provera Shots every three months and they really stopped my hot flashes until I went on Zytiga. Still helped, but not as much.

And then there are the recommendations by the Mayo Clinic doctors. This week’s monthly meeting produced this slide of information about different drugs that work to stop hot flashes

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Replies to "Oxybutynin is one solution. I got depo-provera Shots every three months and they really stopped my..."

@jeffmarc Thanks, Jeff! I've been taking Mirabegron (Myrbetriq) 50 mg unsuccessfully for urinary frequency, as well as having hot flashes. My urologist is considering 5mg Oxybutynin BID for both urinary frequency and hot flashes, but mentioned potential side effects of dry mouth, constipation, and cognitive loss. He commented that if Myrbetriq had been working well, he would have added venlafaxine for controlling hot flashes. I'm typically up at night 4-5 times, with 2 or more of those accompanied by hot flashes as well as throughout the day.