@ss52 Yes, I have seen this and many other articles like it many times. I do not believe it for a minute. Statins cause mitochondrial dysfunction, period. Most people are able to tolerate it, but not everyone. I think the level of pain experienced is proportional to the amount of exercise people engage in. The workout routines I followed when I was on statins were very intense, focused, and consistent. I still maintain that kind of level to this day but with lighter weights and swimming instead of running.

Key Details on Statins and Muscle Mitochondria:

Mechanism of Muscle Damage: Statins may inhibit mitochondrial function and reduce CoQ10 levels, which can cause free radical damage in muscle tissues, commonly termed SAMS.

Symptoms: Reported symptoms include pain, cramps, stiffness, and weakness, often during or after exercise.

Prevalence: While, clinical trials often report low rates, real-world studies suggest 10% to 25% of patients experience muscle issues.

I did come across an article about twenty years ago of a study done exclusively on competitive athletes. It was a small study of about forty people, but the conclusion was that 90% of them could not tolerate statins. Obviously, that study was not funded by big pharmaceutical companies and I have never found it again.

I see my cardiologist on Tuesday and he is the only doctor I have had over the years who completely agrees with me about this issue.

Update: Still no side effects from Repatha after seven months.