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Forteo (teriparatide) followed by HRT: My Experience
Osteoporosis & Bone Health | Last Active: 1 day ago | Replies (190)Comment receiving replies
Hi Mayblin. I was so interested in your post. I am 67 and my dr wants to start me on Forteo. I have just started a transdermal estrogen only patch but dr says it is not enough. My hips are -3.3. I am afraid of the bisphosphonates and was wondering if I continue the transdermal estrogen if hopefully that would be enough to maintain my possible gains from Forteo. I understand that ur not a dr but you seem to be knowledgeable in this area and have experience with the drugs so I thought I would try and ask you what your thoughts were. I appreciate any help or suggestions that you may have. Thank you! : )
Replies to "Hi Mayblin. I was so interested in your post. I am 67 and my dr wants..."
@goseve
For many postmenopausal women under especially 60, Hormone Replacement Therapy (HRT) can be an effective option to maintain bone mineral density (BMD) gains made after a course of Forteo (teriparatide), as noted by the Royal Osteoporosis Society (ROS) and other experts. While bisphosphonates are traditionally used, studies indicate HRT provides comparable fracture reduction and acts as an effective, safe, and inexpensive treatment for bone preservation in younger postmenopausal women.
Some research:
https://pmc.ncbi.nlm.nih.gov/articles/PMC4702457/).
https://pubmed.ncbi.nlm.nih.gov/11341338/
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@goseve
Estrogen is an antiresorptive so it can help slow bone loss and may help maintain gains after an anabolic like Forteo, depending on the individual. In my case, i used estrogen for maintenance after Forteo, and so far, so good.
With a hip Tscore around -3.3, many doctors may feel estrogen alone isn't enough as a starting therapy, even though it may still play a role later on. That's likely why your doctor is recommending Forteo.
If you do decide to go ahead with Forteo, it may be worth asking your doctor how they usually handle estrogen during anabolic treatment - whether it's continued, adjusted, or timed differently, so you're clear on the overall plan from the start.
Please keep us updated and good luck!