Connect
← Return to What's your experience with Orgovyx (relugolix)?
Discussion
What's your experience with Orgovyx (relugolix)?
Prostate Cancer | Last Active: Mar 17 5:59pm | Replies (277)Comment receiving replies
@michaelcharles I hope you’re still active or will be notified about this question. My husband had Gleason 9, 4+4, RP but PSA never came down to undetectable. At first PSA follow up it was 1.5. Then 1.9, 2.0, and 2 months later 2.4. Plan for Radiation IBRT at Mayo FL for 38 sessions for prostate bed and lymph nodes. Despite PSMA PET and MRI showing nothing. Assuming micro metastasis. RO also ordered 6 months of Orgovyx. Can you tell about some side effects?
was fatigue horrible doing both rad and ADT at same time?
What about gynemastisis (breast enlargement)?
Husband’s radiation is every day at 1:30 p.m. Should he take ADT in morning to get over hot flashes before driving 1:15 to treatment?
Any other suggestions? He is active doing household chores and fixing things, but should he be walking for exercise? Weights? He’s thin already, and the MiraLAX for radiation prep is already causing issues. Concerned about how to feed him healthy to stave off fatigue, a low gas. Foods. Any suggestions?
Replies to "@michaelcharles I hope you’re still active or will be notified about this question. My husband had..."
Connect
@susanocl
1st, sincere best wishes for your husband for successful treatment.
I was 72/73 when I took ADT Orgovyx from Jan to June 2023 with IMRT radiation Mar to April within that time.
Salvage Radiation Treatment (SRT) was not pleasant, however it was not arduous either.
Everyone's experience is different and similar, but we all complete treatment and recover from SRT.
Radiation prep, mostly full bladder and mostly empty rectum, are a challenge and every man has to find what works for him.
I took my Orgovyx in the morning because that is my pattern for medication. I had mild heat flashes and did not find them occurring related to the timing of my ADT.
My primary side effect (SE) was about a 10 - 15% reduction in energy.
I think that it was an extremely important part of my recovery to exercise.
I have always been a walker and my routine is a 45 min neighborhood walk. My walk time increased to 50+ minutes. I also was in the habit of doing light upper body lifts 2 - 3 times per week (15 lbs curls & shoulder presses; 25 lbs bench and tricep pulls).
The radiation portion of treatment was 37 IMRT sessions 66.6 gy total and about half way through, I had bowel irritation (radiation proctitis) which was somewhat painful for me and diarrhea, which required some management.
All of my radiation SEs disappeared 2 - 3 weeks after completion of the radiation.
I do not think that I had breast enlargement (but a treatment friend had a mild case).
I ate my regular diet which includes a lot of vegetables, but few legumes or beans. I cut back on my broccoli and salads.
I also took a GasX many nights.
My tx time was later in the afternoon and my mornings were consumed with managing my bowels.
I was never taken off of the table, but I was warned a number of times about gas.
Bladder management is a challenge and different, and the same, for everyone.
Please feel free to private message me now or in the future if I can provide any additional information.
Best wishes.