Lots of people here have reported dry eyes, dry mouth, and other Sjogren's symptoms, tho not clear that's what they have. Did yr doc say that ET brought on the Sjogren's? Any treatment?

MPN specialists at one of those "ask the expert" things I sometimes dial into note that people with ET are prone to gout. They also note that untreated ET can lead to vonWillebrand's syndrome, clots, and strokes. And people report gastric upsets and circulatory issues due to the effects of ET or HU.

I swear my allergies and rosacea are worse due to age plus the increased histamines due to ET, but docs just increase the meds for that and tell me it's all unrelated.

Some patients, of course, have no symptoms, even after many years, and feel great. This might have something to do with allele burden, diet, weight, co-morbidities, driver mutation, etc. Nobody knows for sure. PV and MF are more serious (life-threatening) MPNs, and they get more attention from researchers.

But v-e-r-y slowly, clinicians are starting to realize that ET is not asymptomatic for everyone, and that quality of life can be affected to some degree for many of us.

Okay, off my soapbox now!