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Tamoxifen side effects are very worrying. Read these studies
I'm on Tamoxifen for 10yrs as I've osteoporosis I can't swap to AIs.
My concerns are my long term brain health.
I've daily have severe headaches, poor concentration, all the usual side effects & none have diminished.
Tamoxifen and mental health
I wish to know what other women feel about this drug & if there are other recent 2024 study reports. Does this drug cause harm to our bodies whilst protecting us from the recurrant cancer? such side-effects of tamoxifen are very concerning when taking for 10yrs.
Please comment , thank you
The link below is of another study & also highlights the problems & issues of Tamoxifen saying "Tamoxifen is
shown to decrease performance on visuospatial, visual, and verbal memory tasks".
Please read below link
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11010888/
brightside21 | @brightside21 | 15 minutes ago
I'm too on Tamoxefen & having extreme brain fog, headaches, depression, poor cognition & concentration...etc...so have been researching & think we should all be very wary of these problems. Studies I've read are not extensive or totally conclusive but are showing up a lot of issues.
Please read this link
https://ascopubs.org/doi/10.1200/JCO.2008.21.3553
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Please talk to your oncologist about your side effects! There are options, like switching to one of the AI hormone blockers or reducing your dosage of Tamoxifen. I started taking 10 mg (half-dose) of Tam on Jan. 1st & I'm doing ok so far. I'm 72. Many people have to switch meds or dosages initially, before finding the right balance. Please reach out to your medical team & advocate for yourself! Sending best wishes!
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2 Reactions@jmab Thank you for your support. I have an appointment next week with a list of concerns.
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2 ReactionsI looked at Brightside's research article, and then tried to find a more recent study on the cognitive effects of going on Tamoxifen. Found this from 2024:
https://pmc.ncbi.nlm.nih.gov/articles/PMC11747089/
It too found cognitive function was affected by Tamoxifen, especially in older women, and possibly dependent on dose. I'm glad there are "Baby Tam" studies of 5 mg going on now in the US. I started at 10 mg, and when my joints started aching 3 weeks in, I lowered my dose to 5 mg. I have Alzheimers issues in my family, so don't want to exacerbate that potential problem, at 76. I tried and found I cannot take AI's nor Fulvestrant, because of severe side effects on Blood pressure and severe leg pain & rash. Hormone blockers seem to be a big challenge for me.
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2 Reactions@rphass, how did your appointment with your oncologist go?
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