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Does anyone else have MGUS?

Blood Cancers & Disorders | Last Active: 1 hour ago | Replies (1124)

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@theadosi

Hi Thea (and everyone), I have IGG Lambda and was diagnosed 2 1/2 years ago. It was a random finding that I questioned regarding IGG being elevated, which the doctor said it was nothing to worry about! My IGM and IGA were in the normal range. However, I questioned why it was high and she referred me to a Hematologist/Oncologist for further investigation. All my numbers have been stable so far. My IGG has gone up a little and my FLC ratio is low. My M-Spike was 1.1 in August 2025, down from 1.3 in January 2025.
I go in tomorrow for my 6 month panel of tests, like all of us, but I have not had a BMB as of yet, and since my numbers have been basically ok, I have been opting out of having it. Also, my new Hematologist/Oncologist Professor from John Hopkins Hospital has not been pressuring me to get this done right now. There isn't any treatment for MGUS anyway, which we know, until you progress. I am sure I have had MGUS for many, many years and did not know it. If you don't mind me asking, have you ever had a BMB done? What is your FLC ratio and your M-Spike?

It is great to be able to post on this group and get feedback! You can never have enough knowledge to help make the right decisions when it comes to your health and many other things in life that we experience along our journey!

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Replies to "@theadosi Hi Thea (and everyone), I have IGG Lambda and was diagnosed 2 1/2 years ago...."

@roosa1005 hey there! My M spike was .2 G/DL. Is yours 1.1 G/L? Or 1.1 G/DL? I haven’t had a bone marrow biopsy yet but I just got diagnosed a week ago. I’m assuming they’re waiting to see what my numbers come back as in six months to see if they go up at which point perhaps they’ll order a bone marrow biopsy? I had an MRI of my back done recently as I have some lower back issues that are unrelated and they said that my bone marrow looked good. So I guess that’s good news. My free light chain ratio is .7, what about you? I agree, it is nice to have others who understand and can help ease the worry a little bit!