Hi @juelie Stopping Hydroxyurea (HU) cold turkey is generally not recommended without first speaking with your hematologist/oncologist.
There are other members in the forum who have had take a ‘hydroxy holiday’ however, and have shared their experiences in this discussion.

Hydroxy holiday
https://connect.mayoclinic.org/discussion/hydroxyurea-holidays-how-long-have-you-paused/
Hopefully you’ll be able to get some valuable insights with reading through the conversations. Feel free to pop in anywhere to ask questions.

Wishing you a quick recovery from the MOHs surgery. We also several discusses with other members who have had this surgery for melanoma/skin cancers. Here is a link to the search results where you can tap into a relevant conversation.
https://connect.mayoclinic.org/search/
Is this you first experience with this surgery?