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New study: Early treatment with interferon can delay myelofibrosis
Blood Cancers & Disorders | Last Active: 10 minutes ago | Replies (13)Comment receiving replies
Do you think it is for ET reasonable as well to take interferon?
Replies to "Do you think it is for ET reasonable as well to take interferon?"
In studies, Besremi has been successfully used for ET. It has been shown to reduce the allele burden and reduce the risk of thrombotic events.
https://www.targetedonc.com/view/ropeginterferon-alfa-s-supplemental-bla-moves-on-as-pdufa-date-issued
https://www.oncnursingnews.com/view/ropeginterferon-alfa-2b-effective-in-phase-3-essential-thrombocythemia-trial
So it is possible it could be approved in the next year.
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@birgitr Important question, and no one really knows. The study above indicates that it may not work very well for patients with the more rare CALR mutation. The trade off between side effects and benefits of interferon may not be worth it for some patients. Research goes slowly because our disease is rare, and there are fewer of us to enter trials and studies.