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← Return to MRI before biopsy, & then fusion biopsy if targets found (?)
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MRI before biopsy, & then fusion biopsy if targets found (?)
Prostate Cancer | Last Active: Jan 23 2:26pm | Replies (24)Comment receiving replies
I guess my question is how likely is clinically significant cancer to be found after a systemic biopsy (lets say transrectal) when a Pirads 1 or 2 MRI found nothing suspicious to target? Wouldn't the approach to dealing with a localized 3+3=6 or 3+4=7 (with a small percentage of 4) still be continued active surveillance?
Replies to "I guess my question is how likely is clinically significant cancer to be found after a..."
@ezupcic YES!
@ezupcic YES! What is the PSA at this time?
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@ezupcic
I'm open to being wrong, but I agree with what you are saying, because MRI has better sensitivity than conventional US.
The following is an exaggeration on my part, but it helps me remember the difference between sensitivity and specificity:
MRI has better SENSITIVITY than conventional US (finding true positives - all nodules that are even possibly cancerous will be visible - you'll have lots of targets, but if you target all of them you'll obliterate the prostate).
Conventional ultrasound has better SPECIFICITY than MRI (finding true negatives - only nodules that are obviously cancerous will be visible - you might miss some, but by limiting the number of targets, you won't obliterate the prostate).
It's "systematic" not "systemic", btw.🙂