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Anyone in this clinical trial for low-dose Tamoxifen (LoTam)?
Breast Cancer | Last Active: May 11 5:00pm | Replies (36)Comment receiving replies
At my request my onco gave me the CYP2D6 test, which determines how well I would metabolize Tam. Should I need to take it she will dose accordingly. Meanwhile I get a Guardant Reveal test every three months to detect cancer cell presence. So far so good. FWIW: I strongly encourage second opinions + doing your own research. I brought the CYP2D6 test to my onco’s attention, then she researched it. Cancer is a business and medicine in this country is driven by big pharma. I realized that to achieve my desired outcomes I must be my own project manager, researching options, managing risks, and coordinating efforts among siloed medical fields (e.g. GI, onco, nutrition). Blessings and hearty encouragement to you all because YOU are your own best advocate.
Replies to "At my request my onco gave me the CYP2D6 test, which determines how well I would..."
@maryliz22503 yes, it's big business. I'm 72, stage 1 & had 5-day radiation plus also taking a half-dose (10 mg) of Tamoxifen. My radiologist told me that most of the trials for evaluating the 5-day radiation therapy were done in England because the US medical establishment objectd to the fact that it would be less profitable. Even though it's wonderfully convenient & has fewer side effects! That speaks volumes, doesn't it?!
@maryliz22503
Thanks for sharing this information! It has been my understanding that CYP2D6 determines if Tamoxifen is the most effective drug for an individual versus the actual dosing.
@maryliz22503 :
Thank you so much the information regarding CYP2D6, and Guardant Reveal test.
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@maryliz22503 Thank you for your comment! My onco doc never mentioned these tests and I voiced many concerns with her about the dosing of the AI's!