@kittygrrrl I experienced some nausea and reduced appetite when I began Tymlos. In about 5 months I lost around 15 pounds—no dieting. It was a bonus—I needed to lose weight. The doctor gave me med for the nausea—which lasted a couple of months. By the end of my Tymlos 2 years—I had regained about half of weight lost. Hope you can get back to your normal weight! Hang in there!