@hipsu5, I am also a member of the myeloproliferative neoplasm (MPN) club. My condition is called Polycythemia vera (PV). PV is an ugly sister of your ET and in the MPN family. In May of 2018 I was diagnosed with PV after a routine blood test with platelets in the 685,000 range. Fast forward to 2026. I take one 500 Hydroxyurea (HU) every morning. I call this "Chemo in a pill." I have little or no symptoms. I am determined not to let this condition rule my life. I thought my diagnose was the end, it turned out to be a new beginning for me. I go to my gym 3 times a week, I stay active with my veteran's organizations and am on my American Legion Honor Guard detail. I am a volunteer for Hosparus where I visit veterans on hospice. I have fatigue every evening. Is that from PV or just being an old timer? Who knows? Today is my 67th birthday. Everyday is a new adventure. Long live the fighters!