Although genetic testing is important it is also very difficult to obtain for a specific situation or individual.
After a PCI I was proscribed Clopidogrel which is activated primarily after being metabolized by hepatic cytochrome CYP2C219 enzyme. Individual who lack this enzyme cannot metabolize clopidogrel and should be taking a different P2W12 platelet inhibitor.

The test has been available for this genetic variable for more than a decade but it is nearly impossible to get this test in most parts of the USA. As a result I chose to take ticagrelor instead as it is not affected by this genetic aspect.

Many people will develop blood clots who are taking clopidogrel but it is not going to be ascribed to this
medication being a prodrug that cannot be processed by the individual's liver. This is ignored by the majority of cardiologists who continue to proscribe clopidogrel to their PCI patients.