@dmdinapoli81 As the administrator of a board myself, I am well aware of how threads tend to drift. That seems a little harsh, however. While there are of course diagnostic criteria, the MGUS/SMM/MM spectrum is a continuum, and lines can get a little blurry on the borders.

I'm an example. Technically I've been high-risk MGUS for nearly two years. I've had three marrow biopsies during that time, because my doctor (a hem/onc whom I like a lot) keeps expecting to find >10% plasma cell involvement. Hasn't happened yet. However, a recent 24-hour urine showed significantly-increased albuminuria and bence jones proteinuria, and prompted a kidney biopsy (next week); the results may mean that I start treatment. The chart now notes SMM despite BMB results; MGRS is also in the mix.

It's a complex disease.