Anyone have experience with new fibromyalgia drug Tonmya that came Aug

Tonmya is a reformulated version of the drug cyclobenzaprine (aka Flexeril) that has been on the market for years as a muscle relaxant. It's available as a low cost generic. Tonmya is that same drug reformulated to a lower dose (2.5mg I think) and taken subliminally rather than as a pill you swallow. By reformulating the drug, the drug company can charge lots more money (approximately $250 per month.). When I have a fibro flare, I take a 5mg tablet of cyclobenzaprine (lowest dose available) before bed. I think it helps with sleep and pain.

An article by Pradeep Chopra, MD (a Harvard-trained pain medicine specialist with over 25 years of experience treating complex chronic pain and multisystem disorders) said: "In summary, sublingual cyclobenzaprine (Tonmya) is essentially a repackaged low‑dose formulation of cyclobenzaprine, marketed as a novel drug through its patented delivery system. Its pharmacokinetic differences are small, its clinical benefit is modest and comparable to existing oral formulations, and its unique adverse effects may outweigh the theoretical advantage of reduced metabolite formation. Clinicians should therefore critically evaluate manufacturer claims and consider whether simple, low‑dose oral cyclobenzaprine would provide equivalent benefit at far lower cost."

I also take low-dose Naltrexone which has helped me tremendously. It has to be purchased from a compounding pharmacy and isn't covered by insurance. You slowly work up to a maintenance dose of 4.5mg. There are very few side effects and it takes a few months on the maintenance dose to notice results.

Tonmya is a reformulated version of the drug cyclobenzaprine (aka Flexeril) that has been on the market for years as a muscle relaxant. It's available as a low cost generic. Tonmya is that same drug reformulated to a lower dose (2.5mg I think) and taken subliminally rather than as a pill you swallow. By reformulating the drug, the drug company can charge lots more money (approximately $250 per month.). When I have a fibro flare, I take a 5mg tablet of cyclobenzaprine (lowest dose available) before bed. I think it helps with sleep and pain.

An article by Pradeep Chopra, MD (a Harvard-trained pain medicine specialist with over 25 years of experience treating complex chronic pain and multisystem disorders) said: "In summary, sublingual cyclobenzaprine (Tonmya) is essentially a repackaged low‑dose formulation of cyclobenzaprine, marketed as a novel drug through its patented delivery system. Its pharmacokinetic differences are small, its clinical benefit is modest and comparable to existing oral formulations, and its unique adverse effects may outweigh the theoretical advantage of reduced metabolite formation. Clinicians should therefore critically evaluate manufacturer claims and consider whether simple, low‑dose oral cyclobenzaprine would provide equivalent benefit at far lower cost."

I also take low-dose Naltrexone which has helped me tremendously. It has to be purchased from a compounding pharmacy and isn't covered by insurance. You slowly work up to a maintenance dose of 4.5mg. There are very few side effects and it takes a few months on the maintenance dose to notice results.

Tonmya is a reformulated version of the drug cyclobenzaprine (aka Flexeril) that has been on the market for years as a muscle relaxant. It's available as a low cost generic. Tonmya is that same drug reformulated to a lower dose (2.5mg I think) and taken subliminally rather than as a pill you swallow. By reformulating the drug, the drug company can charge lots more money (approximately $250 per month.). When I have a fibro flare, I take a 5mg tablet of cyclobenzaprine (lowest dose available) before bed. I think it helps with sleep and pain.

An article by Pradeep Chopra, MD (a Harvard-trained pain medicine specialist with over 25 years of experience treating complex chronic pain and multisystem disorders) said: "In summary, sublingual cyclobenzaprine (Tonmya) is essentially a repackaged low‑dose formulation of cyclobenzaprine, marketed as a novel drug through its patented delivery system. Its pharmacokinetic differences are small, its clinical benefit is modest and comparable to existing oral formulations, and its unique adverse effects may outweigh the theoretical advantage of reduced metabolite formation. Clinicians should therefore critically evaluate manufacturer claims and consider whether simple, low‑dose oral cyclobenzaprine would provide equivalent benefit at far lower cost."

I also take low-dose Naltrexone which has helped me tremendously. It has to be purchased from a compounding pharmacy and isn't covered by insurance. You slowly work up to a maintenance dose of 4.5mg. There are very few side effects and it takes a few months on the maintenance dose to notice results.

@daisy17 One post from you gives me more info than I’ve gotten in a year from my doc (I just switched for that reason)! I take Zanaflex at night for muscle pain and have for years. Flexoril has never been mentioned as an option for my severe fibromyalgia pain. My neurosurgeon prescribed it for back pain until I could have surgery but I’m going to ask my new doctor what she thinks, as well as Naltrexone, which I’ve never even heard of! Thank you so much.😊

@daisy17 One post from you gives me more info than I’ve gotten in a year from my doc (I just switched for that reason)! I take Zanaflex at night for muscle pain and have for years. Flexoril has never been mentioned as an option for my severe fibromyalgia pain. My neurosurgeon prescribed it for back pain until I could have surgery but I’m going to ask my new doctor what she thinks, as well as Naltrexone, which I’ve never even heard of! Thank you so much.😊

Tonmya is a reformulated version of the drug cyclobenzaprine (aka Flexeril) that has been on the market for years as a muscle relaxant. It's available as a low cost generic. Tonmya is that same drug reformulated to a lower dose (2.5mg I think) and taken subliminally rather than as a pill you swallow. By reformulating the drug, the drug company can charge lots more money (approximately $250 per month.). When I have a fibro flare, I take a 5mg tablet of cyclobenzaprine (lowest dose available) before bed. I think it helps with sleep and pain.

An article by Pradeep Chopra, MD (a Harvard-trained pain medicine specialist with over 25 years of experience treating complex chronic pain and multisystem disorders) said: "In summary, sublingual cyclobenzaprine (Tonmya) is essentially a repackaged low‑dose formulation of cyclobenzaprine, marketed as a novel drug through its patented delivery system. Its pharmacokinetic differences are small, its clinical benefit is modest and comparable to existing oral formulations, and its unique adverse effects may outweigh the theoretical advantage of reduced metabolite formation. Clinicians should therefore critically evaluate manufacturer claims and consider whether simple, low‑dose oral cyclobenzaprine would provide equivalent benefit at far lower cost."

I also take low-dose Naltrexone which has helped me tremendously. It has to be purchased from a compounding pharmacy and isn't covered by insurance. You slowly work up to a maintenance dose of 4.5mg. There are very few side effects and it takes a few months on the maintenance dose to notice results.

@daisy17 My dr at mayo said the same thing about tonmya. He gave me 5mg flexeril to take at night since I have $0 generics. It helps a lot.