If anyone is having a Reclast infusion soon, please be sure to begin these things a day or two before, day of, and a day or two after: lots of hydration, Tylenol, and your choice of antihistamine. All of these help to minimize the potential acute phase reactions. Reading the side effects can be daunting, but keep in mind that the FDA is required to list any side effect reported even if it's rare. And of course, any other health issues you may have could possibly affect how your body responds. Make sure your infusion is at least 30 minutes, preferably 45 for some of us. I learned so much about the Reclast infusion from this group, and I am grateful for the tips shared by patients who had a positive experience. It made all the difference for me, and I'm praying that continues when I have my second one this summer. We are all in this together!