@rodney9999 I was put on a Protein Pump Inhibiter as a protocol medication post transplant to prevent acid reflux and heartburn symptoms. I was told the lack of stomach acid can then produce lower GI concerns so then was given Senna to prevent those problems. I did not experience heartburn or acid reflux so I started researching the medication prescribed and discovered that there was a 20mg version rather than the 40mg version prescribed, so I called the pharmacy and asked if they could work with the doctor to change the dose. Once on 20mg I still didn't have acid reflux or heartburn so I asked at my next visit if I could remove the medication and my doctor agreed. As soon as I stopped the Protein Pump Inhibitor (PPI) meds I also was able to stop using Senna for the GI side effects. If you are symptom free check with your team to see if you can change things up. I have found that doctors are very receptive to trying things out if you present a compelling case for yourself. Good luck.