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@jlam1950

There are different forms of vaginal Estradiol that aren't messy. They would be Vagifem and Imvexxy suppositories. There's vaginal DHEA suppositories called Intrarosa that converts to estrogen and testosterone.

Yeah, so far the Estradiol gel is helping. Compounding pharmacies can give you alternatives like a wrist roll-on device or a spray.

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@blueskies1530

There are also pellets which are inserted just below the skin. Also, estradiol patches and compounded testosterone cream that is applied to the skin