I'm almost 50 and am three months post-hysterectomy. Prior to hysterectomy, I was wearing a low-dose Estradiol patch for hot flashes, headaches and joint pain. After hysterectomy, the patch was not enough for my symptoms, especially the joint pain and genitourinary symptoms so my gynecologist switched me to an Estradiol gel at a 1.25mg dose. I rub it behind my knees and on my wrists everyday as it works more slowly and the patch more quickly. It's still not enough for my vaginal symptoms so I use other things for that and if you want to discuss it I can.

For something natural prior to hysterectomy, I did take a break from Estradiol and find hot flash relief using a bottle of Soy Isoflavone capsules purchased at Sprouts or Amazon. I tried Estroven as well that you can buy in a grocery store. It contains Rhapontic Rhubarb and Isoflavones. But because I was having so many terrible symptoms I reverted to Estradiol but this time to a gel with my gynecologist's help.

I see a NP at a separate practice who runs bloodwork every 2-3 months to monitor my hormone and other levels.

I hope this helps and am happy to discuss further.