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jlam1950 avatar

Why not hormone replacement therapy for elderly patients?

Menopause | Last Active: Apr 22 12:01pm | Replies (19)

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Profile picture for mcchesney @kathleen1314

Yes, most of us have come to the point where we balance quantity of life vs quality of life
Mini strokes/strokes and HRT and BHRT
Bioidentical Hormone Replacement Therapy (BHRT), especially when using transdermal (skin-applied) estradiol, appears to have a lower stroke risk than traditional oral HRT, which is linked to increased clotting; transdermal routes bypass the liver, reducing clotting factors, while bioidentical progesterone may also be safer than synthetic progestins, making the delivery method and type of hormone crucial factors in stroke risk.
It seems that the safest way to administer any hormone therapy is via topical, bypassing the liver and bioidentical which the body recognizes since it is well , bioidentical, ha.
https://www.epicresearch.org/articles/blood-clot-risk-influenced-by-hormone-therapy-administration-route-in-women-50-and-older
https://www.ahajournals.org/doi/10.1161/strokeaha.117.017132.
Conclusions—
In a national setting, we found an increased risk of stroke, based on ischemic stroke, with oral hormone therapies that was comparable to findings from randomized studies. We found no risk of stroke with transdermal application and a reduced risk with vaginal estrogen.

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Replies to "Yes, most of us have come to the point where we balance quantity of life vs..."

@kathleen1314

I am so glad that you brought up the issue of quality of life vs quantity of life. At 76 that is exactly why I choose to start bhrt after being denied this kind of care for decades due primarily to the flawed women's health initiative study. I wanted to feel alive again. I wanted my libido to return. I was not afraid and I am still not afraid of any of the possible side effects. POSSIBLE!
When I die I will be grateful that these two things were restored to me.