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Osteoporosis & Bone Health | Last Active: Apr 1 8:30pm | Replies (10)
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@mundy
Congratulations! Your new Tscores show improvements at all three sites (lumbar spine, total hip, and femoral neck), which is impressive overall after 1yr of Tymlos, especially since the hip and femoral neck are typically the hardest areas to improve.
If you have the actual BMD values (g/cm2), you can calculate the percent change using
(BMD2025 - BMD2023) /BMD2023 x 100%
Some DXA reports generate the BMD % change for us.
Somewhere in the DXA report (often in the footnote) the Least Significant Change (LSC) is listed. If your BMD change is greater than the LSC, then the change is considered statistically significant rather than due to normal machine-related variation.
Replies to "@mundy Congratulations! Your new Tscores show improvements at all three sites (lumbar spine, total hip, and..."
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@mayblin
I am looking for the LSC you reference but cannot find anything on any of the 3 DEXA reports I have since 2022. The reports are Hologic. This 'normal variation' number would seem to be very helpful for many of us with small numerical changes.