Walking pneumonia led to lung nodule to lung mass! 2 biopsy this week

Posted by medtech4 @medtech4, Dec 7, 2025

I had walking pneumonia over the summer. I went on antibiotics but scan showed rather large nodule and ground glass appearance. Biopsy was done and it was negative. This was in September. Then, I go for a follow up scan in early November and nodule, well, really, mass has gotten a tiny bit bigger, but ground glass appearance has cleared. The mass is the size of a business card! It's 4 cm by 8 cm! It was not really much different from the one in September but they want to biopsy it again. Will be doing that this week. I'm hoping it's still benign, but its size is so concerning. I do cough a little. That's really my only symptom. Lung surgery is really a major endeavor, but I don't don't what can be done except to hope it just goes away. With my history, I'm guessing it's infectious or inflammatory. I had a PET scan and it lit up, but so did a bump on my head that I got a week before the scan! Any advice?

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We are all with you during this fight.

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Thank you. Your support means so much to me. It really does. No one else knows what this is like than those who have gone through a similar diagnosis. I feel like I'm struggle to stay above water. It's a nightmare. I have my first treatment on Friday. I'm so scared of the after effects.

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Profile picture for Lisa, Volunteer Mentor @lls8000

@medtech4, I'm glad that your tests came back quicker than expected, and that they identified a targetable mutation. The targeted therapies can be a game changer where treatments are concerned. I see that they are starting you on chemo too. Of course, make sure the team is proactive with the anti-nausea meds. They should help! I wonder if the Tagrisso may help with the head pain. Did your doctor give you an idea of how long it would take to notice results from the meds and chemo? When I started my targeted therapy, for ALK not EGFR, I could tell it was working in the first week because I started feeling better and could breathe easier.

There are others with EGFR exon19 deletion in the lung cancer group too. You'll see some of their comments in these discussions too. @flusshund, Matthew is a long-term EGFR survivor.
Here are couple of links to discussions that may be helpful.
https://connect.mayoclinic.org/discussion/tagrisso-for-lung-cancer/
https://connect.mayoclinic.org/discussion/carboplatin-plus-permetrexed/

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@lls8000 On Dec. 31, I had a radiation treatment for the head. I had a lot of pain afterwards, but I took a steroid and it eased. Now, over a week later, the pain has decreased and the bump has shrunk! I see the interventional radiologist again on Feb. 2. I see the oncologist on the 14th for a follow up and scheduled for my next chemo on the 23rd. I imagine the effects are cumulative for the chemo. But I have all the meds with renewals, so I'll be ready. (at least physically) Sorry I haven't replied sooner, but it's taken some time to process all this.

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