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How long have you been on Orgovyx (relugolix)?
Prostate Cancer | Last Active: Jan 9 12:02pm | Replies (44)Comment receiving replies
@rnpalarino1 With PSA rising following prostatectomy (indicating likely recurrence), but PSMA showed no signs of cancer either (1) the PSMA PET scan missed it (at a PSA of 0.9, PSMA will miss prostate cancers ~30% of the time), or (2) your prostate cancer is PSMA negative, in which case a PSMA PET scan will never see the cancer.
Note that while you’re on ADT (and your PSA is being suppressed), the PSMA PET scan won’t be able to see the prostate cancers.
If your prostate cancer is PSMA positive, either Pluvicto (Lutetium-177) or Xofigo (Radium-223) might kill the cancer (depending on where it is).
If your prostate cancer is PSMA negative, an Axumin (F18-Fluciclovine) PET CT scan might see the prostate cancer that the PSMA PET scan can’t.
You might consider discussing this with your doctor rather than remaining only on hormone therapy.
Replies to "@rnpalarino1 With PSA rising following prostatectomy (indicating likely recurrence), but PSMA showed no signs of cancer..."
@brianjarvis
A big reason tumors are missed When a PSMA scan is done is because the scan can’t see the smaller ones.
The scan cannot see metastasis smaller than 2.5 mm and one of the doctors at UCSF said that even a 5 mm metastasis a is hard to see and is missed many times.
That’s probably the main reason it is 30%.
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@brianjarvis
I appreciate your comments. I trust my oncologist from Mayo Clinic. However just to confirm his treatment plan I was also seen by an oncologist at Johns Hopkins who agreed with Mayo on treatment plan.