@chorusgirl500 My Jak2 was positive and my doctor and I decided together that the bone biopsy would not be needed and my treatment, Hydroxyurea and phlebotomies would be the same no matter what the results of a biopsy said. Being JAk2 negative is really a good thing! You may have an underlying condition and can be treated.PV Primary is with JAK2 + PV secondary means something else could be causing it and sometimes it can be resolved! Did they say they believe it is PV? Have you been traveling in High Altitudes? It can raise all your blood levels and mimic PV labs. Your ins is much better than mine. I have a high annual ded. And then I pay 20% of all costs. I was never sick and always healthy so I get it. You are so young and will get it all figured out. Please keep us all posted and if you have any questions, just ask.