@db72 Phoenix Rising member also. 33 years with ME/CFS for me .. I have much respect for someone 40 years in. I offer my honesty, experience and empathy - it's all I have. Personally, I am no longer searching for a medication or treatment. Since around year 15, I have been making the slow transition from longevity of life to quality of life. Some (Medical Pros and also forum members) have suggested that this is "giving up". For me, it's the opposite of that. Everyone more or less has to find their own path. I have meditated (in my own custom manner) for over 70,000 hours in the last 30 years; it has been invaluable, and it is my main coping skill. However, I have no intention of presuming that what works for me, would work for anyone other than myself. These forums tend to have alot of 'try this med' kind of advice, which kind of makes my head spin. Maybe this is similar to what you are feeling.