Creatinine levels

Hello:

I had a kidney transplant last year. What has helped me is a plant-based diet. I do take both vitamins. I hope that is helpful.

Tokunbo

@jeffdeif•••General guidelines (not medical advice)•••

With a creatinine of 1.98 and eGFR around 35 (CKD stage 3b), supplements should be chosen carefully.

✓Vitamin D3
Often appropriate in CKD, especially if levels are low (which is common).
Low-dose vitamin D3 (for example 800–1,000 IU daily) is commonly used if blood calcium and phosphorus are normal.
Vitamin D should ideally be taken based on a blood 25-OH vitamin D level, not blindly.
Excess vitamin D can raise calcium levels, which can be risky in CKD.

✓Vitamin K2
Vitamin K2 does not significantly affect kidney function.
It does not increase bleeding risk when taken with aspirin or Effient.
K2 is sometimes used alongside vitamin D to help direct calcium to bones rather than blood vessels.
Avoid only if on warfarin (Coumadin) — which you are not.
*Important cautions*
Do not take high doses of either supplement without provider approval.
Avoid combination supplements that include calcium, phosphorus, magnesium, or potassium unless cleared by your doctor.
CKD patients should recheck:
✓Calcium
✓Phosphorus
✓PTH (parathyroid hormone)
✓Vitamin D level

Many people with CKD stage 3 can take low-dose vitamin D3 and K2, but it’s safest when:
✓Dosing is modest
✓Labs are monitored
**When the prescribing doctor (cardiology or nephrology) is aware**

Source's:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022248/ — Discusses guidelines and why vitamin D supplementation is often used in CKD patients with low vitamin D levels �
PMC

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999920/ — Explores how vitamin D and vitamin K relate to bone health in CKD �
PMC

https://www.kidney.org/kidney-topics/vitamins-chronic-kidney-disease —

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099759/ — �
PMC

https://www.karger.com/kbr/article/46/5/523/824458/Role-of-Vitamin-K-in-CKD-Is-Its-Supplementation — �
Karger Publishers

“Vitamin D supplementation is often recommended in people with CKD who are deficient”
“Vitamin K2 status is commonly low in CKD, and supplementation appears safe **but not definitively proven to improve outcomes**
“Always discuss vitamin supplements with your doctor when kidney function is reduced”.

*Disclaimer*

Nothing contained in this reply constitutes, reflects, or implies my personal opinion; it is provided exclusively for informational purposes only. This information is subject to further investigation, interpretation, and clarification and is not a substitute for professional advice from a licensed medical specialist.

The content is compiled from sources commonly considered reputable and reliable, but it should be understood that such sources may change, be updated, or be subject to revision, and no representation of absolute accuracy is made.

@jeffdeif It would be good to get bloodwork to see if you are deficient in any vitamins firt, including D3 and B vitamins. Consider getting off NSAIDS (aspirin), which are very hard on kidneys, even in low doses. If you are on supplements it is good to review them with your nephrologist or other specialist (CKD affects what we can eat, drink, and otherwise take).

I agree with the caution about taking low-dose aspirin. I am almost 74 and had Holep surgery about four years ago after having urine back up into my bladder and caused kidney damage. I am at stage 3A/B. I was told by the doctors that the benefit I might get from taking low-dose aspirin for possible heart issues is out weighed by the further damage to my kidneys taking aspirin risks. This may vary from patient to patient depending on their other medical problems, I suppose, but I would definitely check with my nephrologist and primary physician about the pros and cons of taking low dose aspirin.