@lls8000 Yes. They did some genetic tests on the lung biopsy sample. The oncologist also took blood samples for biomarkers on Wednesday, the 17th. They used Guardant. It's reassuring that people are living years after their diagnosis. My biggest fear is losing "me" in all this, especially with the brain affected. I want to remain cognizant of my surroundings and able to communicate. I have head pain that the doctor said will lessen with radiation. That will probably begin after the New Year. The doctor will be away the first week in January, but I may begin with his P.A., or wait, because those genetic markers will come back and we'll know how better to move forward. Your support has been helpful to me. I don't know who to share this diagnosis with. Only my closest friends and family know (about 10 people). I may tell a neighbor or two that we talk to often. We don't really "hang out" with them, but we talk.

@lls8000 I was going to start Keytruda Xmas eve, but when I went in, the doctor showed me new information about a biomarker that I had and it just came in. Now, there's a new plan. He showed me an article he printed out from NEJM about stage IV lung cancer with metastases to the brain and the statistics were somewhat encouraging. So, I'm starting on cisplastin, Pemetrexed, both chemo and Tagrisso (targeted). I have an EGFR mutation- thr Exon 19 deletion and PD-L1 22C3 of 80% , being over 50% is good. So, I'm hoping for the best but dreading the side effects especially vomiting. I haven't thrown up since I was 12 years old and I'm 67!!! So this is the plan beginning Jan. 2. I have a lot of head pain where there is cancer on the skull and brain. I have a radiologist consult to see if it can help with my pain. I don't know if it can fit in with the other plan or not.