Hi, @soggybones I chose to begin MHT after my osteoporosis diagnosis though I have increased risk of breast cancer. Was diagnosed with LCIS at the age of 47 and took tamoxifen for 2.5 years. Diagnosed with osteoporosis at 52.

After reading everything I could find online, I scheduled an appointment for a risk / benefit conversation with my oncologist. We focused on menopause symptoms as I discovered most non-bone specialist docs don’t really like to talk MHT for OP treatment, just prevention. My oncologist and I agreed that the potential benefit is worth the risk for me. It’s important to note that I am screened twice a year, alternating mammograms with MRIs. The thinking is if a cancer does develop, we have a good shot at catching it early.

In my most recent annual visit to my oncologist, she suggested that I look at and consider switching to duavee. I’ll likely do this at some point, but have been hesitant to change just yet as the patch and progesterone have been working well for me.

There are two particular bits of reading you may find interesting. One is a book, Estrogen Matters. The other is the PROMISE study which looks at Duavee as potentially reducing the risk of breast cancer in women with DCIS.

Best of luck to you as you navigate this decision. It is such a highly personal choice and so much depends on your own risk / benefit assessment as well as your personal comfort level.