Hello @huronshores. You may notice I moved your discussion and combined it with another discussion titled, "Side effects of hydroxyurea, ET." I did this so a few of the members discussing the same topic would have a chance to see your message. I'd like to also invite @pearly and @wasbilly back to this discussion. @huronshores, have you considered getting a second opinion or discussing this issue with a pharmacist, who may be more familiar with the side-effects and potential issues it can cause? It is best to stop a medication under the advisement of a pharmacist or physician, so it may be worth your time raising the issue again to make sure you are doing so safely.