I too have had a long journey with knee problems... starting with arthroscopy surgery in my twenties (I am now 66). I have done multiple rounds of prolo therapy, PRP injections, autologous stem cell injections - all very expensive and the results did not last. The best things I have done are Arthrosamid and Whole Body Vibration. For the Arthrosamid, I flew to Canada last year. It was about $3000 USD, and it has worked incredibly well. My once weak knee is now my strong knee! Halleluiah! I can now do a one-legged squat, with my other foot resting on that knee, and then jump up and down with all my weight on the knee that crippled me for most of my life. I have also been doing Whole Body Vibration for 25 years and have found it to be incredibly helpful for all kinds of joint and nerve problems (I had many debilitating joint and nerve issues). Within days of starting Whole Body Vibration, I saw my pain and inflammation levels drop and other things like my immune system and my mood improved. It is important to use the right WBV machine for you though. There are many different kinds of machine and they are not all the same. It has very powerful effects on the whole body. For example, you don't want to use a machine designed for an Olympic athlete if you are older and have some health issues. With Arthrosamid, WBV, plus eating well and HIIT (High Intensity Interval Training workouts which I've been able to take up since getting Arthrosamid), I feel fantastic! I am so much stronger and more active than I have ever been before. I am so grateful to finally be able to do the activities I love and enjoy.